醫學四：80題 ( 包括小兒科,皮膚科,神經科,精神科等科目及其相關臨床實例與醫學倫理 )題庫下載題庫

Subacute combined degeneration — Deficiency in vitamin B12 (cobalamin) leads to degeneration of the dorsal and lateral white matter of the spinal cord, producing a slowly progressive weakness, sensory ataxia, and paresthesias, and ultimately spasticity, paraplegia, and incontinence]. Not all patients with neurologic abnormalities will have anemia or macrocytosis. Supplemental treatment with vitamin B12 can stop progression and will produce neurologic improvement in most patients.

Nitrous oxide abuse can also lead to subacute combined degeneration, by inactivation of vitamin B1...

Subacute combined degeneration — Deficiency in vitamin B12 (cobalamin) leads to degeneration of the dorsal and lateral white matter of the spinal cord, producing a slowly progressive weakness, sensory ataxia, and paresthesias, and ultimately spasticity, paraplegia, and incontinence]. Not all patients with neurologic abnormalities will have anemia or macrocytosis. Supplemental treatment with vitamin B12 can stop progression and will produce neurologic improvement in most patients.

Nitrous oxide abuse can also lead to subacute combined degeneration, by inactivation of vitamin B12