55下列藥品配對中,何者會產生藥效學交互作用(Pharmacodynamic i..-阿摩線上測驗
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2F Bryan 國三上 (2014/07/17)
Verapamil increases digoxin levels significantly in most patients. Verapamil decreases renal and extrarenal clearance of digoxin. Serum digoxin levels may increase by 50% to 75% during the first week of concomitant verapamil therapy. Increases may be larger in patients with hepatic cirrhosis. Digoxin and verapamil have additive effects in slowing AV conduction. In clinical trials with digitalized patients with atrial fibrillation or atrial flutter, 15% of patients developed ventricular rates of less than 50/min and 5% developed asymptomatic hypotension.... 查看完整內容 |
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