58.下列何者不會增加metformin引起lactic acidosis的風險？
(A)alcohol
(B)vitamin B₁₂
(C)topiramate
(D) parenteral contrast media

答案：登入後查看
統計： A(118), B(4961), C(283), D(264), E(0) #2180262

詳解 (共 10 筆)

正能量的黑天鵝

B1 · 2020/02/16

#3783438

使用metformin的副作用包...

(共 226 字，隱藏中）

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160

最後的Lunch

B4 · 2020/07/23

#4168080

可能造成乳酸中毒 : metformin...

(共 255 字，隱藏中）

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107

maomao

B3 · 2020/07/22

#4166133

注射顯影劑要停用的：NSAID, Met...

(共 45 字，隱藏中）

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Mr. Drug

B2 · 2020/07/08

#4126812

Lactic acidosis: [US Boxed Warning]

Risk factors for lactic acidosis include patients with renal impairment, concomitant use of certain drugs (eg, carbonic anhydrase inhibitors such as topiramate), ≥65 years of age, having a radiologic study with contrast, surgery and other procedures, hypoxic states (eg, acute heart failure), excessive alcohol intake, and hepatic impairment.

(B) Long-term metformin use is associated with vitamin B12 deficiency; monitor vitamin B12 serum concentrations periodically with long-term therapy.

(D) 補充：病患注射放射性顯影物質做檢查前後各2天+當天需停用Metformin。