阿摩線上測驗
60.40歲男性人類免疫不全病毒(HIV)感染者,體重65公斤,服用抗反轉錄病毒治療2年,服用組合為
lopinavir/ritonavir(蛋白酶抑制劑)+tenofovir/emtricitabine(核苷反轉錄酶抑制劑),CD4+T細胞數600
cells/μL,HIV病毒量＜20copies/mL,潛伏結核(latenttuberculosis)檢查為陽性，若要接受潛伏結核治療,
且不改變抗反轉病治療,則下列何種處置最為恰當?
(A)每天isoniazid300mg,治療9個月
(B)每天isoniazid 300 mg +rifampin600mg,治療3個月
(C)每天rifampin600 mg+pyrazinamide 1,500mg,治療2個月
(D)每週isoniazid 900mg+rifapentie900mg,治療12週
答案：登入後查看
統計： A(396), B(124), C(28), D(44), E(0) #2741671
統計： A(396), B(124), C(28), D(44), E(0) #2741671
詳解 (共 2 筆)
chin8941
#6038028
Latent TB Infection and HIV
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1. Twelve weeks of once-weekly isonaizid and rifapentine (3HP), given by self-administered therapy or directly observed therapy, is the newest CDC-recommended treatment regimen for persons with latent TB infection and HIV and who are taking antiretroviral medications with acceptable drug-drug interactions with rifapentine.
2. Four months of daily rifampin is another treatment option. This regimen should not be used in people with HIV who are taking some combinations of antiretroviral therapy. In situations where rifampin cannot be used, sometimes another drug, rifabutin, may be substituted.
3. For those taking antiretroviral medications with clinically significant drug interactions with once-weekly rifapentine or daily rifampin, nine months of daily isoniazid is an alternative treatment.
2. Four months of daily rifampin is another treatment option. This regimen should not be used in people with HIV who are taking some combinations of antiretroviral therapy. In situations where rifampin cannot be used, sometimes another drug, rifabutin, may be substituted.
3. For those taking antiretroviral medications with clinically significant drug interactions with once-weekly rifapentine or daily rifampin, nine months of daily isoniazid is an alternative treatment.
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