62.下列何者為最合適的給藥方式?
(A)靜脈注射每6小時1次
(B)腹腔內給藥,每日1次,並留在腹腔內至少6小時
(C)每日早上口服1次
(D)腹腔內給藥,每日4次,並留在腹腔內至少6小時
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統計: A(338), B(3236), C(122), D(1762), E(0) #1837881
統計: A(338), B(3236), C(122), D(1762), E(0) #1837881
詳解 (共 3 筆)
#3474422
腹膜透析感染,用腹腔內給藥是效果最好,副作用又少
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#4874209
根據ISPD PERITONITIS RECOMMENDATIONS: 2016 UPDATE
抗生素的給與方式有兩種,以cefazolin 為例
Intermittent : 15–20 mg/kg daily (每天一次
Continuous : LD 500 mg/L, MD 125 mg/L (每袋透析液都要給藥
也有提到In intermittent dosing, the antibiotic-containing dialysis solution must be allowed to dwell for at least 6 hours to allow adequate absorption.
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另外順便提醒一下 ciprofloxacin 是可以用在腹膜炎的 附上ISPD原文
Oral administration of fluoroquinolones is commonly used alone or in combination with other antibiotics (237).
Oral ciprofloxacin and moxifloxacin reach adequate levels within the peritoneum (293,323). However, adequate IP levels may require a day to be reached, and some oral phosphate binders
can bind fluoroquinolones and reduce their bioavailability
can bind fluoroquinolones and reduce their bioavailability
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