67.樹突細胞可以誘導調節性T細胞的分化，下列那個分子與此功能無直接關聯？
(A)IL-10
(B)TGF-β
(C)Indoleamine 2, 3 dioxygenase（IDO）
(D)IL-6

答案：登入後查看
統計： A(50), B(33), C(64), D(164), E(0) #1324564

詳解 (共 2 筆)

#1426928
IL 6: causes fever and stimulates production of acute-phase protein
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#2891985

 Increasing  expression  of  the  anti-inflammatory  enzyme  indoleamine 2,3-dioxygenase (IDO) by treatment with IFN-γ or by unmethylated CpG DNA can induce the generation or activation of Treg  cells. 

Tumors can produce enzymes that act to suppress local immune responses. The enzyme indoleamine 2,3-dioxygenase (IDO) catabolizes tryptophan, an essential amino acid, in order to produce the immuno suppressive metabolite  kynurenine.  IDO  seems  to  function  in  maintaining  a  balance between  immune  responses  and  tolerance  during  infections,  but  can  be induced during the equilibrium phase of tumor development. 

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