7. Which one of the following molecules is used as a calcineurin inhibitor?
(A) Cyclosporin A
(B) Daidzen
(C) Genistein
(D) PP1
(E) Wortmannin.

8.Which one of the following molecules is NOT involved in Toll-like signaling (A) IRF3 (B) MyD88 (C) NFkB (D) Syk (E) TRIF.

9. Which is NOT the protective response against infectious agent induced by the immune system? (A) Effector function (B) Recognition (C) Regulation (D) Memory (E) Tolerance.

10.Which immune cell form a key link between the innate immune system and the adaptive in (A)B cell (B) Dendritic cell (C) ILC (D) NK cell (E) T cell.

11. Which isotype of immunoglobulin transports across placenta? (A)IgA (B) IgD (C) IgE (D) IgG (E) IgM

12. Which isotype of immunoglobulin sensitizes NK cells? (A)IgA (B) IgD (C) IgE (D) IgG (E) IgM

13. Which is NOT the event of cellular immune responses? (A) Antibody-mediated cellular cytotoxicity (ADCC) (B) Cytokine secretion (C) Granzyme/perforin-mediated killing (D) Neutralization (E) Phagocytosis.

複選題14. Which one of following features is the characteristic of class II MHC molecule? (A) Accommodates peptides of 10-30 residues (B) CD4 binds mainly to the o1 domain (C) Locations of polymorpbic residues are a1 and o2 domains (D) Nomenclatures are HLA-A, -B, -C in human (E) Polypeptide chains are a and Bz-microglobulin.

15. Which one of following features is the characteristic of class II MHC pathway of antigen processing and presentation? (A) B1, 32 and B5 subunits of proteasomes are responsible for protein degradation (B) CD8+ TI cells are responsive T cells (C) Endoplasmic reticulum (ER) is the site of peptide loading to MHC. (D) Late endosomes and lysosomes are the site of antigen degradation (E) TAP1/2 molecules are involved in peptide transport and loading.

複選題16. Which one of followings is a component of class II MHC pathway of antigen processing and presentation? (A) Aminopeptidase ERAAP (B) HLA-DM (C) LMP7 (D) MECL-1 (E) Tapasin.

17. Which one of the following factors is involved in negative selection of T cell development? (A) CD8 co-receptor (B) Hassall's corpuscle (C) Macrophage in the medulla (D) MHC class I/II (E) Peptides on MHC class III.

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