上面詳解都沒回答到(D),以一篇review article內容解釋: Medication-induced intracranial hypertension There is a strong association with tetracycline usage. Minocycline and doxycycline have also been linked to PTC, although there are relatively few reported cases. PTC has also been described with retinoids, including vitamin A (retinol) and isotretinoin. tetracyclin與isotretinoin都是會造成顱內高血壓的藥物,因此(D)併用會加重是合理的