70.Digoxin與下列何者併用時,無須調降digoxin劑量?
(A)amiodarone
(B)quinidine
(C)rifampin
(D)verapamil

答案:登入後查看
統計: A(151), B(208), C(4604), D(460), E(0) #1541410

詳解 (共 7 筆)

#2294658

(C)RIFAMPIN增加肝酵素代謝 但digoxin不是肝代 所以下降跟肝代沒有關係 micromedex交互作用↓20%digo level 作用 未知

不要沒查就亂回答喔~

 

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#2558093
Digoxin是由p-glycoprot...
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#4063372
P-gp的抑制劑:有Amiodarone...
(共 103 字,隱藏中)
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#3445337
抑制P-gp,使Digoxin濃度上升。...
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#3464802
有查到Rifampin會誘導P-gp 會...
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#3465643

DDI- Rifampin & Digoxin

Micromedex: (major, good)

Probable mechanism unknown

UpToDate: (moderate, fair)

P-glycoprotein/ABCB1 Inducers may decrease the serum concentration of P-glycoprotein/ABCB1 Substrates. P-glycoprotein inducers may also further limit the distribution of p-glycoprotein substrates to specific cells/tissues/organs where p-glycoprotein is present in large amounts (e.g., brain, T-lymphocytes, testes, etc.).

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#2191268
(A)Amiodarone會抑制CYP3...
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