112年 - 112 國立清華大學_碩士班考試入學試題_生命科學暨醫學院甲組(生物與醫學科學組)：生物化學#117747

科目：研究所、轉學考(插大)◆生物化學 | 年份：112年 | 選擇題數：20 | 申論題數：0

試卷資訊

所屬科目：研究所、轉學考(插大)◆生物化學

選擇題 (20)

1. To synthesize one molecule of palmitate from acetyl-CoA and malonyl-CoA, how many electrons are involved? (A) 12, (B) 16, (C) 28, (D) 18,(E) 32.

2. The driving force(s) for fatty acid biosynthesis from acetyl-CoA (A) ATP, carboxylation, decarboxylation, (B) ATP, carboxylation, decarboxylation, NADH, (C) ATP, NADPH, decarboxylation, (D) ATP, NADH, carboxylation, (E) ATP, carboxylation, decarboxylation, NADPH.

3. Regarding transaldolase and transketolase, (A) both transfer 1-carbon unit, (B) both transfer 2-carbon unit, (C) both transfer 4-carbon unit, (D) transaldolase transfers 2-carbon and transketolase transfers 3-carbon, (E) transaldolase transfers 3-carbon and transketolase transfers 2-carbon.

4. Glycolysis is enhanced by (A) fructose-1,6-bisphosphate,(B) glucose-1-phosphate, (C) fructose-2,6-bisphosphate, (D) glucose-6-phosphate and fructose-1,6- bisphosphate,(E) fructose-1,6-bisphosphate and fructose-2,6-bisphosphate.

5. Edman degradation will: (A) determine the C-terminal amino acid by using a carboxypeptidase, (B) cleave the protein into a multitude of smaller peptides, (C) compare overlapping sets of peptide fragments, (D) determine the N-terminal amino acid, (E) generate two different, but overlapping sets of peptide fragments.

6. What is the overall net charge on the peptide "LKGDGARE" at pH 7.0? (A) +2,(B) +1,(C)0,(D)-2,(E)-1.

7. The large negative free energy change of ATP on hydrolysis is due to: (A) destabilization due to electrostatic repulsion, (B) stabilization of products by ionization and resonance, (C) entropy factors arising from hydrolysis and ionization, (D) free energy change ~35kJ/mol, (E) all of the above.

8.Which amino acid acts as a helix breaker due to its unique structure? (A) Histidine, (B) Tyrosine, (C) Arginine, (D) Serine, (E) Proline.

9. Which enzyme is not involved the carbon fixation of the Calvin cycle in C4 plants? (A) Fructose-1,6-bisphosphatase, (B) NADP-dependent malic enzyme,(C)Pyruvate phosphate dikinase (PPDK), (D) NADP-malate dehydrogenase, (E) Phosphoenolpyruvate carboxylase (PEPC).

10. Which descriptions about the non-cyclic photophosphorylation is not correct? (A) PSI and PSII are involved, (B) electron travels back to PSI, (C) electron from PSII is accepted by NADP⁺, (D) ATP is produced, (E) water splitting is involved.

11. After glycolysis, the generated pyruvate must be oxidized into which molecule before entering the TCA cycle? (A) succinyl-CoA, (B) nicotine adenine dinucleotide, (C) coenzyme A, (D) acetyl-CoA, (E) ATP.

12. Which process releases dinitrogen gas (N₂) back into the atmosphere? (A) Denitrification,(B) nitrogen fixation, (C) decay, (D) nitrification, (E) nitrogen assimilation.

13. If an error is made during replication that is not caught by DNA polymerase, the most likely is that________. (A) both strands of DNA will be mutated (B) only the daughter strand will be mutated (C) a mutation that causes cancer will occur (D)DNA ligase will repair the mistake before a mutation occurs (E) DNA replication will stall indefinitely

14. Homeotic genes encode which type of protein? (A) transcription factors (B) ribosomal proteins (C) channel proteins (D)membrane-associated proteins (E) DNA methylases

15. As the polypeptide is elongating during translation, what is the ribosome doing? (A)removing incorrectly added amino acids (B) moving along the mRNA transcript bonding amino acids to each other (C) travelling back and forth between the nucleus and the growing polypeptide with information on which amino acids to add (D) removing the noncoding introns (E) breaking hydrogen bonds between the tRNA and the mRNA

16. How do steroid hormones differ from those derived from amino acids? (A)Steroid hormones are not derived from organic molecules. (B) Steroid hormones do not bind to plasma membrane receptors. (C) Steroid hormones use a second messenger system. (D) Steroid hormones do not travel in the blood. (E) Steroid hormones do not require receptors to function.

17. Cholesterol is the precursor for the following lipids, EXCEPT_______. (A) cortisol, (B) estradiol, (C) cholic acid, (D) progesterone,(E) cardiolipin.

18. Which lipid is not the major component of biological membranes? (A) lysophospholipid, (B) phosphatidylcholine, (C) phosphatidylethanolamine, (D) sphingolipid, (E) cholesterol.

19. Myristoylation is a lipid modification of protein. Where is the amide-linked myristoyl anchor attached to? (A) N-terminal Lys (B) N-terminal Gly, (C) C- terminal Asp, (D) C-terminal Cys, (E) Ser.

20. Which one is not a diastereomer of D-glucose? (A) D-galactose, (B) D-mannose, (C) L-galactose, (D) D-ribose,(E) L-Idose.

申論題 (0)