試題詳解

12. Which of the following statements is true for gene transcription in the eukaryotes?
(A) Tfg2 is the second largest subunit of TFIIF and is homologous to bacterial alpha-subunit of RNA polymerase.
(B) Mediator is a collection of proteins that is a part of most RNA polymerase II preinitiation complexes and is not required for transcription initiation, but is required for activated transcription.
(C) TFIIIA is a general transcription factor for RNA polymerase III and contains 9 zinc finger structures in which one finger containing 6 cysteines to coordinate 2 zinc ions.
(D) In the absence of ligand, the thyroid hormone receptor exists as an inactive form in cytoplasm complexed with heat shock protein 90.

(E) Silencers are DNA-binding proteins that can cause strong bending in DNA.