試題詳解

15. Organophosphate poisoning has been reported in cases of accidental ingestion of contaminated food. Which of the following best describes the toxic mechanism of organophosphates?
(A) Irreversible inhibition of acetylcholinesterase, leading to excessive accumulation of acetylcholine at synapses.
(B) Blockade of dopamine receptors, resulting in impaired neurotransmission.
(C) Competitive inhibition of gamma-aminobutyric acid (GABA) receptors, causing excessive neuronal excitation.
(D) Inhibition of sodium-potassium ATPase, leading to disruption of cellular ion homeostasis