16. Which of the following statements about type II restriction enzymes is(are) false?1. They are sequence-specific DNA endonucleases.2. Many make staggered (off-center) cuts within their recognition sequences. Some cut DNA to generate blunt ends.3. They cut both DNA strands at the same base pair.4. They are part of a bacterial defense system in which foreign DNA is cleaved.5. The size of the DNA region specifically recognized by type II restriction enzymes is typically 8 to 12 base pairs.(A) 1 and 3 are false.(B) 2 and 4 are false.(C) 3 and 5 are false.(D) Only 4 is false.(E) Only 5 is false.