16. Which of the species below is/are more basic than acetylide? (I) CH3Li, (II) CH3ONa, (III) CH；MgBr, (IV) NaOH, (V) KOH. (A)I only (B) II only (C) III only (D) I and II (E) II and IV.

2. Physostigmine is used in the treatment of glaucoma. Within this structure, the atom indicated by is most basic, while atom is least basic. (A) 1 (most basic), 4 (least basic) (B) 1 (most basic), 3 (least basic) (C) 2 (most basic), 4 (least basic) (D) 2 (most basic), 3 (least basic) (E) None of the above.