試題詳解

17. Which of the following statements correctly describes a key difference between microRNAs (miRNAs) and small interfering RNAs (siRNAs)?
(A) miRNAs primarily regulate gene expression through translational repression, while siRNAs often induce mRNA cleavage when binding to their target.
(B) miRNAs typically bind to perfectly complementary sequences on target mRNAs, while siRNAs bind to partially complementary sequences.
(C) siRNAs are derived from endogenous transcripts, while miRNAs are always of exogenous origin.
(D) Both miRNAs and siRNAs are loaded onto the RNA-induced silencing complex (RISC), but only siRNAs recruit the Argonaute protein.
(E) miRNAs are processed in the cytoplasm by Dicer, while siRNAs are processed exclusively in the nucleus.