2. Which one of the following elements is most likely to form a 1+ ion?
(A) aluminum
(B) indium
(C)thallium
(D) boron
(E) gallium

78.微衛星的不穩定性（microsatellite instability, MSI）程度與接受化療藥物5-fluorouracil（5-FU）效果相關。關於 MSI檢測，下列何者最不適當？ (A)MSI可使用毛細管電泳或Genescan分析 (B)當腫瘤組織與正常組織的PCR產物長度差異10 bp，則該MSI標記點為陰性 (C)當腫瘤組織有超過30%的MSI標記點為陽性時，認定為高度MSI（MSI-high） (D)高度MSI（MSI-high）病人，接受5-FU治療效果不佳

79.Oxaliplatin廣泛使用於腸胃道相關惡性腫瘤的治療上，其治療效果與ERCC1基因表現量有關，ERCC1在細胞 內主要之功能為何？ (A)加快細胞週期 (B)修復損傷之DNA (C)促進DNA複製 (D)抑制血管新生

80.表皮生長因子受體（epidermal growth factor receptor, EGFR）基因突變是肺癌常見的突變之一，該基因的突變 最常發生在下列那個區域？ (A)酪胺酸激酶區域（tyrosine kinase domain） (B)穿膜區域（transmembrane domain） (C)膜外區域（extracellular domain） (D)表皮生長因子結合區域（EGF binding domain）

1. How many significant figures does the difference 218.7201 – 218.61 contain? (A) 1 (B) 2 (C) 3 (D) 4 (E) 5

3. Name the compound CuSO4 (A) Copper (I) sulfate (B) Copper (II) sulfate (C)Copper (II) sulfite (D) Cobalt (II) sulfate (E) Cobalt (II) sulfite

4. A mass spectrometer works by ionizing atoms or molecules, and then accelerating them through oppositely charged plates. The mass is obtained by (A) measuring the force of impact on a detecting screen, and then calculating the mass using force = mass × acceleration. (B) suspending the ions in an applied electric field, and then calculating mass by the setting the downward gravitational force equal to the upward electrostatic force. (C)measuring the magnitude of deflection as the ions pass through a magnetic field to obtain the charge-to-volume ratio, and then calculating the mass from that ratio. (D) measuring the time it takes for the ions to hit the detector at a known distance to calculate the acceleration, and then calculating mass from force = mass × acceleration. (E) all are not correct.

5. Which of the following compounds is a strong acid? (A) HF (B) HI (C)HClO2 (D) H2SO3 (E) HNO2

6. How many total electrons are transferred in the following reaction? (A) 2 (B) 3 (C)4 (D) 6 (E) 12

7. A 45 mL sample of nitrogen gas is cooled from 135ºC to 15°C in a container that can contract or expand at constant pressure, what is the new volume of the nitrogen gas? (A) 64 mL (B) 5.0 mL (C)410 mL (D) 32 mL (E) 41 mL

8. Styrene, C8H8, is one of the substances used in the production of synthetic rubber. When styrene burns in oxygen to form carbon dioxide and liquid water under standard-state conditions at 25°C, 42.62 kJ are released per gram of styrene. Find the standard enthalpy (kJ/mol) of formation of styrene at 25°C. (Given: ) (A) ~141.28 (B) ~317.28 (C)~636.7 (D) ~4249 (E) ~8730