22. Mesothelioma is not found with
(A) Asbestos bodies are found in increased numbers in the lungs of patients with mesothelioma
(B) The tumor cells show strong immunoreactivity to TTF-1 protein
(C) Mesothelioma is usually associated with extensive pleural effusion and direct invasion
(D) The affected lung becomes ensheathed by a thick layer of soft, gelat a soft, gelatinous, grayish pink tumor tissue
(E) The most common cytogenetic abnormalities is homozygous deletion of chromosome 9p leading to loss ofthe tumor suppressor gene CDKN2A.