22. Which of the following statements about Surface-Enhanced Raman Scattering (SERS) are correct? (A) SERS significantly enhances Raman signals by using nanostructured non-metal surfaces, typically silica (B) The enhancement in SERS arises mainly from two mechanisms: electromagnetic enhancement and chemical enhancement. (C) SERS requires that the analyte molecule has a permanent dipole moment to exhibit enhancement. (D) The electromagnetic enhancement in SERS is primarily due to surface plasmon resonance in nanostructures. (E) SERS enables detection of very low concentrations of analytes.