阿摩線上測驗
3.下列何種cytotoxic agents之致吐風險為低風險等級（10%～30%）？
(A)carmustine
(B)dacarbazine
(C)mechlorethamine
(D)paclitaxel
統計： A(311), B(456), C(1061), D(4192), E(0) #1528134
詳解 (共 10 筆)
似乎烷化劑的抗癌藥比較容易致吐~(ABC都屬這類)
anthracycline類多屬中致吐
| 高 | 中 | 低 | 微 |
Anthracycline/cyclophosphamide for breast cancer Carmustine Cisplatin Cyclophosphamide ≥1500mg/m2 Dacarbazine Mechlorethamine Streptozocin | Alemtuzumab Azacytidine Bendamustine Carboplatin Clofarabine Cyclophosphamide<1500 mg/m2 Cytarabine >1000 mg/m2 Daunorubicin* Doxorubicin* Epirubicin* Idarubicin* Ifosfamide Irinotecan, liposomal irinotecan Oxaliplatin Romidepsin Temozolomide Thiotepa Trabectedin | Aflibercept Bortezomib Brentuximab Carfilzomib Catumaxumab Cetuximab Cytarabine≤1000 mg/m2 Docetaxel Eribulin Etoposide Fluorouracil Gemcitabine MethotrexateΔ Mitomycin Mitoxantrone Paclitaxel and nab-paclitaxel Panitumumab Pegylated liposomal doxorubicin Pemetrexed Pertuzumab Temsirolimus Topotecan Ado-trastuzumab emtansine | Bevacizumab Bleomycin Busulfan 2-Chlorodeoxyadenosine Cladribine Fludarabine Nivolumab Ofatumumab Pembrolizumab Pixantrone Pralatrexate Rituximab Trastuzumab Vinblastine Vincristine Vinorelbine |
單一化學治療藥物致吐風險分為四級
高致吐性 >90%
carmustine ndacarbazine mechlorethamine
中致吐性 30%-90%
doxorubicin
低致吐性 10%-30%
paclitaxel
輕微致吐性 <10%
nnnnnnnnnnnnnnnn
bleomycin
paclitaxel 主要是會過敏
cisplatin已改為不分劑量都是高致吐了
阿摩的口訣
高致吐： 我開大車順著圓環繞十圈，超想吐！ 我(MEchlorethamine)開大(DActinomycin)車(DaCARbazine, CARmustine, CARboplatin)順(CISplatin)著圓環(CYCLOphosphamide)繞十(Streptozocin)圈，超想吐！
