34. How many disulfide bonds does a normal insulin have?
(A) 1
(B) 2
(C) 3
(D) 4

35.Which of the following lipoprotein undergoes the RNA editing process to produce lipoprotein apo B-48? (A) Apolipoprotein A1 (B) Apolipoprotein C (C) Apolipoprotein B100 (D) Apolipoprotein E

36. Which of the following statements about eicosanoid hormones is correct? (A) Most are preformed and stored in vacuoles close to the cell membrane within the cell. (B) Prostaglandin, thromboxanes and leukotriene are not all their derivatives (C) Among them, thromboxanes are related to red blood cell (RBC) production. (D) The raw materials required for its production and synthesis mainly come from the cell membrane and are hydrolyzed by the enzyme phospholipase A2.

37. In the synthesis of gonadal hormones, which enzyme is unique to the production of estrogen? (A) Aromatase (B) 5a-reductase (C) 17a-hydroxylase (D) 20a-hydroxylase

38. Which of following amino acid has high rigidity led to for a natural kink in the peptide? (A) Glycine (B) Proline (C) Serine (D) Cysteine

39. Which of the following proteins cannot promote bone marrow hematopoiesis? (A) Granulocyte colony-stimulating factor (G-CSF) (B) Abciximab (C) Erythropoietin (D) Romiplostim

40. Mipomersen is an antisense oligonucleotide therapy for homozygous familial hypercholesterolemia through reducing serum low density lipoprotein (LDL) level. Which of the following is its main suppress target? (A) Proprotein convertase subtilisin/kexin type 9 (PCSK9) (B) Apolipoprotein E (C) Apolipoprotein B-100 (D) Apolipoprotein Al

41. Interleukin (IL)- 11 is a hematopoietic growth factor and mainly regulates the growth of which of the following? (A) Red blood cell (RBC) (B) Reticulocyte (C) Platelet (D) Monocyte

42. In the TCA (tricarboxylic acid) cycle, which of the following is the only dehydrogenase that does not use NAD+ as a coenzyme? (A) a-Ketoglutarate dehydrogenase (B) Malate dehydrogenase (C) Isocitrate dehydrogenase (D) Succinate dehydrogenase

43. Vitamin K deficiency can cause coagulopathy. What modifications are required for many coagulation factors? (A) ẞ-Acetylation (B) y-Carboxylation (C) B-Carboxylation (D) y-Acetylation

44. Many of the most potent toxins found in nature. Which of the following is the intoxication mechanism of tetrodotoxin? (A) Activating acetylcholine receptor (B) Antagonizes acetylcholine receptors (C) Blocks voltage-gated K+ channels (D) Blocks voltage-gated Na+ channels

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