試題詳解

41. Which of the following statements about AMP-activated protein kinase (AMPK) is incorrect?
(A) AMPK activity is allosterically regulated by AMP and ATP.
(B) Binding of AMP to AMPK promotes the phosphorylation of the enzyme, and thus enhances the enzyme activity.
(C) Regulation of AMPK activity involves a pseudosubstrate sequence, which is a molecule structurally related to AMP.
(D) Metformin, an anti-diabetic drug, exerts its effects through AMPK activation.
(E) One ofthe effects of AMPK activation is stimulation of fatty acid oxidation.