試題詳解

5. 一位 48 歲女性，診斷有 high grade lymphoma，預定接 受 cytotoxic chemotherapy。病人目前的 serum creatinine level 是 2.1 mg/d。為了預防發生 tumor lysis syndrome 及腎臟惡化，下列處置，何者最適宜?
(A) Give allopurinol or febuxostat, if not contraindicated, for preventing hyperuricemia
(B) Give acetylcysteine for preventing acute kidney injury
(C) Give large amount of 5% glucose water solution for volume expansion
(D) Give 1,25-activated Vitamin D3 for preventing hyperphosphatemia
(E) Arrange dialysis immediately after chemotherapy for preventing occurrence of chronic interstitial nephritis