5. Which of the following description regarding the rearrangement of both TCR and BCR gene
segments is NOT correct?
(A) Generate diversity of antigen binding by recombination of a large pool of germline V, D, and J
segments.
(B) Lead to CDR3 being the most hypervariable region in the receptor chains.
(C) Require RAG-1 and RAG-2
(D) Require TdT
(E) Result in isotype switching after antigen stimulation of the mature lymphocytes
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