50.下列有關hydralazine的敘述,何者錯誤?
(A)降血壓的主要作用機轉為抑制angiotensin II受體
(B)結構中含有phthalazine環
(C)N-Glucuronide為其代謝物之一
(D)O-Glucuronide為其代謝物之一
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統計: A(3202), B(92), C(286), D(279), E(0) #415092
統計: A(3202), B(92), C(286), D(279), E(0) #415092
詳解 (共 9 筆)
#3170862
補充:長期使用易造成SLE(紅斑性狼瘡)之藥品:(常考)
(1)Hydralazine
(2)Procainamide (class 1A抗心律不整=Arrhythmia)
(3)Propylthiouracil (抗甲狀腺亢進藥)
40
0
#994647
Hydralazine
(Apresoline(R)) is a direct-acting smooth muscle relaxant used to treat
hypertension.
18
1
#865448
phthalazine
17
1
#865445
Hydralazine
11
1
#865444
Although the precise mechanism of action of Hydralazine is not fully understood, the major effects are on the cardiovascular system. Hydralazine apparently lowers blood pressure by exerting a peripheral vasodilating effect through a direct relaxation of vascular smooth muscle. Hydralazine, by altering cellular calcium metabolism, interferes with the calcium movements within the vascular smooth muscle that are responsible for initiating or maintaining the contractile state.
0
6