6.下列那一種情況對於trimethoprim-sulfamethoxazole的治療感受性最低?
(A)無併發症之革蘭氏陰性菌感染
(B)Salmonella引起的胃腸炎
(C)Pneumocystis carinii引起的呼吸道感染
(D)肺結核菌
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統計: A(611), B(535), C(329), D(2693), E(0) #442566
統計: A(611), B(535), C(329), D(2693), E(0) #442566
詳解 (共 6 筆)
#1098630
Co-trimoxazole(Baktar® )為Sulfamethoxazole:Trimethoprim =5:1,能有效治療泌尿道與呼吸道感染,還可用於AIDS的肺囊蟲肺炎(PJP)及毒漿體病(Toxoplasmosis)。
肺結核第一線藥物
Isoniazide ㊀mycolic acid合成
Rifampin ㊀DNA-dependent RNA polymerase
Ethambutol ㊀arabinosyl transferase
Pyrazinamide ㊀mycolic acid合成
Streptomycin ㊀核醣體30S
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#891996
Co-trimoxazole 用於治療H.influenzae及肺鏈球菌引起的呼吸道感染
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#891994
Trimethoprim/sulfamethoxazole or co-trimoxazole is an antibiotic used in the treatment of a variety of bacterial, fungal and protozoal infections. It consists of 1 part trimethoprim to 5 parts sulfamethoxazole. Co-trimoxazole is generally considered bactericidal, although its components are individually bacteriostatic. Its actions are antifolate in nature, inhibiting both de novo folate biosynthesis and metabolism.
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