61 下列何種藥物在低劑量下可引起serotonin 的釋放及抑制其再攝取,具有減低食慾及減輕體重之作用?
(A) Ergonovine
(B) Dexfenfluramine
(C) Ketanserin
(D) Bromocriptine

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統計: A(34), B(210), C(161), D(36), E(0) #418407

詳解 (共 4 筆)

#1241482
記住!"5-HT上升;食慾下降"
fenfluramine會增加serotonin濃度;為5-HT receptor agonist
厭食作用最強:d-norfenfluramine
在低劑量下會引起serotonin釋放及抑制其在攝取具有減低食慾及減輕體重作用
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#5473060

Ketanserin is a high-affinity non-selective antagonist of 5-HT2 receptors in rodents,In addition to the 5-HT2 receptors, ketanserin is also a high affinity antagonist for the H1 receptor. It has also been found to block the vesicular monoamine transporter 2 (VMAT2).

常作為降血壓藥物來使用

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#5685401
Dexfenfluramine:引起se...
(共 144 字,隱藏中)
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#824014
Dexfenfluramine, marketed as dexfenfluramine hydrochloride under the name Redux, is a serotoninergic anorectic drug: it reduces appetite by increasing the amount of extracellular serotonin in the brain.
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