63.王先生服用aspirin後,胃部有燒灼感且出現黑便,改用何種藥品最適當?
(A)Clopidogrel
(B)Dipyridamole
(C)Ticlopidine
(D)Warfarin
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統計: A(2808), B(181), C(77), D(197), E(0) #626606
統計: A(2808), B(181), C(77), D(197), E(0) #626606
詳解 (共 7 筆)
#2863794
*thienopyridines : inh P2Y12 receptor of ADP ->antiplatelet
-Ticlopidine: the first drug of P2Y12 receptor antagonist, disadvantage in hematological disorder
-Clopidogrel: =Plavix®, need CYP2C19 actived, irreversibly inh P2Y12
-Prasugrel: prodrug, actived by intestines esterase, irreversibly
-Ticagrelor & Cangrelor : no need actived and metabolite rapidly, reversibly.
9
1
#3436225
(A)Clopidogrel相較於(C)Ticlopidine副作用較少
8
0