76. 下列那一種抗憂鬱藥物，可以透過阻斷α2-腎上腺素型受體的作用方式，來增加腦中的腎上腺素性及血清素性神經傳遞作用？
(A) Bupropion
(B) Mirtazapine
(C) Imipramine
(D) Fluoxetine

答案：登入後查看
統計： A(61), B(262), C(94), D(31), E(0) #559634

詳解 (共 5 筆)

#4694825

Mirtazapine為一 NaSSA(Norepinephrine and Specific Serotonergic 能阻斷 5-HT2與 α2-腎上腺性 受器 它也是 鎮靜劑 。

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#823056
Mirtazapine :Tetracyclic antidepressants
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#6050151
Mirtazapine： 屬於 pipe...
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#821812
Evidence gathered in preclinical studies suggests that mirtazapine enhances central noradrenergic and serotonergic activity. These studies have shown that mirtazapine acts as an antagonist at central presynaptic α2-adrenergic inhibitory autoreceptors and heteroreceptors, an action that is postulated to result in an increase in central noradrenergic and serotonergic activity.
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#823684
Mirtazapine is a potent antagonist of 5-HT2 and 5-HT3 receptors. Mirtazapine has no significant affinity for the 5-HT1A and 5-HT1B receptors.

Mirtazapine is a potent antagonist of histamine (H1) receptors, a property that may explain its prominent sedative effects.

Mirtazapine is a moderate peripheral α1-adrenergic antagonist, a property that may explain the occasional orthostatic hypotension reported in association with its use.

Mirtazapine is a moderate antagonist at muscarinic receptors, a property that may explain the relatively low incidence of anticholinergic side effects associated with its use.
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