80.下列抗癌藥作用機轉係抑制topoisomerase II,但何者除外?
(A)Topotecan
(B)Dactinomycin
(C)Doxorubicin
(D)Mitoxantrone
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統計: A(3132), B(292), C(263), D(453), E(0) #416834
統計: A(3132), B(292), C(263), D(453), E(0) #416834
詳解 (共 8 筆)
#1098990
喜樹鹼衍生物Camptothecins: Irinotecan、Topotecan抑制Topoisomerase I,防止單股斷裂再密合,對S期具有專一性。
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#980212
etoposide 才係抑制topoisomerase II^^
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#4123014
Topoisomerase II = 抑制 S-G2
Topoisomerase I = 抑制 G2-M
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#854732
Topotecan is a chemotherapeutic agent that is a topoisomerase inhibitor. It is a water-soluble derivative of camptothecin. It is used in form of the hydrochloride to treat ovarian cancer and lung cancer, as well as other cancer types.
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