85. Release of succinate from succinyl-CoA can be coupled to GTP synthesis because: (A) Coenzyme A is a "high energy" compound, just like GTP. (B) The link between succinate and CoA involves an acid anhydride to phosphate. (C) The thioester bond between succinate and CoA has a large -AG of hydrolysis. (D) The amide bond between succinate and CoA has a large -AG of hydrolysis. (E) None of the above.

85. Release of succinate from succinyl-CoA can be coupled to GTP synthesis because:
(A) Coenzyme A is a "high energy" compound, just like GTP.
(B) The link between succinate and CoA involves an acid anhydride to phosphate.
(C) The thioester bond between succinate and CoA has a large -AG of hydrolysis.
(D) The amide bond between succinate and CoA has a large -AG of hydrolysis.
(E) None of the above.

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統計： A(5), B(4), C(7), D(1), E(0) #3421190

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83. Sterol regulatory element-binding protein (SREBP) controls the gene expression of cholesterol biosynthesis. What happens when there is the presence of a high cellular concentration of cholesterol? (A) It increases the proteolytic cleavage and releases SREBP into the nucleus. (B) SREBP is hold in the Golgi apparatus in a complex with SREBP-cleavage-activating protein (SCAP) to produce a regulatory domain fragment. (C) It activates SREBP by inducing the conformational change for cholesterol biosynthesis. (D) It stabilizes the SCAP-SREBP complex by the anchoring of insulin-induced gene protein (Insig). (E) SREBP acts as a corepressor of RXR-LXR dimer to terminate the gene expression of cholesterol biosynthesis.

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