9. A mutation causes a gene to become overactive, contributing to uncontrolled cell growth. Which term best describes this gene?
(A) tumor-suppressor gene
(B)oncogene
(C)spliced gene
(D)alternatively spliced gene
(E) malignant gene

5. For heart muscles to beat in a coordinated rhythm ions must move from one cell to the next through ____. (A) desmosomes (B)gap junctions (C)focal adhesions (D)adherens junctions (E) hemidesmosomes 說明：一、請一律以「答案卷」作答，作答時不得使用鉛筆，違者該科答案卷不予計分； 限用黑色或藍色墨水的筆書寫。 二、考生應在答案卷上規定範圍內作答，且不得書寫任何與答案無關之文字、符 號，違者該科不予計分。 三、答案卷以每人一張為限，不得要求增補；試題與答案卷必須繳回，不得攜出 試場。

複選題6. Who discovered that DNA was the genetic material or transforming factor that could convert nonvirulent R-type Streptococcus pneumoniae bacterium to the virulent S-type? (A) Weismann and Nageli (B)Griffith (C)Avery, MacLeod, and McCarty (D)Hershey and Chase (E) Watson, Crick, Wilkins, and Franklin

7. Transcription begins near a site in the DNA called the ______. (A) promoter (B)enhancer (C)response element (D)transcription unit (E) regulatory sequence

8. An mRNA that contains the coding sequence for two or more structural genes is called a (A) polyintronic mRNA (B)polyextronic mRNA (C)polycistronic mRNA (D)polyexpressive mRNA (E) polyrepressor mRNA.

10. Which of the following statements about the cell cycle is correct? (A) The cell cycle is a sequence of replications and divisions that produces a new cells. (B)The phases of the cell cycle are G1, S, and M phases. (C)In actively dividing cells, the S and G2 phases are collectively known as interphase. (D)When the S phase of the cell cycle is finished, a cell has twice as many chromatids as the number of chromosomes in the G1 phase. (E) During G2 phase, the cell grows and copies its chromosomes in preparation for cell division.

11. The probability of obtaining a recessive phenotype from self-fertilization of a heterozygous individual is (A)25%(B)50%(C)75%(D)100%(E)12.5%

12. The inheritance pattern where two or more genes do not assort independently because they are close together on the same chromosome is called (A) Mendelian inheritance.(B)epistasis.(C)genomic imprinting.(D)linkage.(E) dominance.

13. Which one of following pathogens has no genetic materials? (A) a prokaryote (B)a viroid (C)a plasmid (D)a virus (E) a prion

14. What is a homeobox? (A) a cluster of homeotic genes (B)a sequence within a homeotic gene that encodes the DNA-binding portion of a transcription factor (C)the portion of the promoter to which a homeoprotein binds to activate transcription of genes important for development (D)an enhancer region needed for expression of a homeotic gene (E) none of these are correct

15. What nucleic acid is subject to alternative splicing? (A) DNA (B)rRNA (C)pre-mRNA (D)mRNA (E) tRNA