試題詳解

9. Celiac disease ( 麥麩不耐症 ﹚ is a T cell-driven intolerance to gluten ingestion in genetically predisposed people﹒ The gluten﹣derived T cell epitopes are proline﹣rich and thereby highly resistant to proteolytie degradation within the gastrointestinal tract. Which ofthe following descriptions is NOT correct?
(A) Gluten is a mixture of water-insoluble prolamin protein﹒
(B) Prolamins constitute the significant endosperm storage proteins in mature cereal grains.
(C) Upon gluten ingestion, proteases in the gastrointestinal tract degrade gluten proteins into peptides.
(D) Increased prevalence of symptomatic celiac disease can be associated with gut microbiota changes and environmental modification.
(E) The primary therapeutic approach for celiac disease is oral enzyme therapy, employing gluten-degrading enzymes.