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關於手術後急性疼痛處理相關的敘述,下列敘述何者為非?
(A) 術前每天口服60mg以上的morphine 或 8mg以上的hydromorphone,需視為opioid-tolerant patient。
(B) 親脂性的opioid在neuraxial anesthesia比親水性的opioid較少產生噁心嘔吐及皮膚癢的問題。
(C) 親水性的opioid在neuraxial anesthesia可能會有early 及delay onset的呼吸抑制。
(D) 相較於成人患者,含有continuous background dose的 IV PCA對兒童患者有較高的呼吸抑制副作用。
(E) Obstructive sleep apnea病人止痛應考慮使用NSAID or nonopioid adjuvants,以降低呼吸抑制副作用。
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統計: A(1), B(2), C(2), D(12), E(1) #2478396
統計: A(1), B(2), C(2), D(12), E(1) #2478396
詳解 (共 1 筆)
#5577877
D. 2010 meta-analysis 說的
https://pubmed.ncbi.nlm.nih.gov/20297614/
Addition of a background infusion to the demand dose for IV-PCA with opioids was associated with a significant increased risk for respiratory depression (odds ratio [OR] = 4.68, 95% confidence interval [CI]: 1.20-18.21). Subgroup analysis revealed that this increased risk was seen in adult but not in pediatric patients.
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