試題詳解

10. Please choose one correct answer for the roles of different general transcription factors in eukaryotic RNA polymerase I, II and III.
(A) TFIID has a DNA helicase activity that is essential for promoter clearance during transcription.
(B) The 5S RNA genes only require TFIIIB to form a preinitiation complex with the RNA polymerase III.
(C) The asymmetric binding of TFIIA to the promoter can determine the direction of transcription.
(D) The human core-binding factor SL1 is fundamental transcription factor to recruit RNA polymerase I.
(E) TFIIB not only stabilizes TBP and TATA box binding, but also use an antirepression mechanism to stimulate TFIID and promoter binding.