12. Which of the following blood components would interfere with the functioning of an open circulatory system but not a closed one?
(A) red blood cells
(B) antibodies
(C) water
(D) electrolytes
(E) amino acids

8. Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to (A) myosin denaturation and inhibition of cleavage furrow formation. (B) disruption of mitotic spindle formation. (C) inhibition of DNA synthesis. (D) inhibition of regulatory protein phosphorylation. (E) suppression of cyclin production.

9. Because they accumulate in the body, excess ingestion of which of the following can have toxic effects? (A) calcium and phosphorus. (B) fat-soluble vitamins. (C) sugars. (D) water-soluble vitamins. (E) proteins

10. Which of the following statements about the mammalian digestive system is true? (A) Enzyme production continues in the esophagus. (B) All foods begin their enzymatic digestion in the mouth. (C) The trachea leads to the esophagus and then to the stomach. (D) After leaving the oral cavity, the bolus enters the larynx. (E) The epiglottis prevents food from entering the trachea.

11. Pulse is a direct measure of (A) heart rate. (B) stroke volume. (C) breathing rate. (D) blood pressure. (E) cardiac output.

13. HIV targets include all of the following except (A) cytotoxic T cells. (B) cells bearing CD4 and fusin. (C) brain cells. (D) macrophages. (E) helper T cells.

14. Both the eye and the respiratory tract are protected against infections by which of the following? (A) the mucous membranes that cover their surface (B) the secretion of complement proteins (C) the secretion of lysozyme onto their surface (D) interferons produced by immune cells (E) the release of slightly acidic secretions

15. Which of the following is true of ammonia? (A) It has low toxicity relative to urea. (B) It can be stored as a precipitate. (C) It is soluble in water. (D) Only A and C are true. (E) A, B, and C are true.

複選題16. Unlike an earthworm's metanephridia, a mammalian nephron (A) forms urine by changing the composition of fluid inside the tubule. (B) is intimately associated with a capillary network. (C) functions in both osmoregulation and the excretion of nitrogenous wastes. (D) processes blood instead of coelomic fluid. (E) has a transport epithelium.

17. Short blood vessels connect two capillary beds lying in which of the following? (A) anterior pituitary and posterior pituitary. (B) hypothalamus and thalamus (C) anterior pituitary and adrenal gland. (D) posterior pituitary and thyroid gland (E) hypothalamus and anterior pituitary

18. Prolactin stimulates mammary gland growth and development in mammals and regulates salt and water balance in freshwater fish. Many scientists think that this wide range of functions indicates which of the following? (A) Prolactin is a nonspecific hormone. (B) Prolactin is an evolutionary conserved hormone. (C) Prolactin has a unique mechanism for eliciting its effects. (D) Prolactin interacts with many different receptor molecules. (E) Prolactin is derived from two separate sources.