16. A circular 11-nm chromatin fiber contains 100 nucleosomes. If this chromatin fiber are depleted of histone proteins and treated with an endonuclease to produce one single-strand break, what would the DNA look like? (A) a relaxed circular DNA duplex containing about 20,000 base pairs (B) a relaxed circular DNA duplex containing about 2,000 base pairs (C) a supercoiled DNA containing about 100 negative supercoils (D) a supercoiled DNA containing about 100 positive supercoils