23. Gout is caused by ___ over degradation results in accumulation of uric acid.
(A) purine
(B) pyrimidine
(C) fatty acid
(D) glucose
(E) amino acid

19. Dihydrouracil and pseudouridine are found predominantly in ________. (A) mRNA (B) rRNA (C) tRNA (D) Z form DNA (E) siRNA

20. Which oil listed below contains more than 60% unsaturated fatty acids? (A) beef (B) milk (C) coconut (D) palm (E) olive

21. In order to perform PCR, the following reagents must be included ________. (A) DNA fragment, primers flanking the region of interest, dNTPs, ddNTPS, DNA Polymerase (B) DNA fragment, primers flanking the region of interest, dNTPs, DNA Polymerase (C) DNA fragment, one primer, dNTPs, DNA Polymerase, DNA ligase (D) DNA fragment, primers flanking the region of interest, dNTPs, DNA Ligase (E) none of the above

22. The coding sequence of DNA is 5’-CGCTATAGCGTTT-3’. Which of the following sequences is its RNA transcript (mRNA)? (A) 3’-CGCTATAGCGTTT-5’ (B) 5’-CGCUAUAGCGUUU-3’ (C) 3’-GCGATATCGCAAA-5’ (D) 5’-UUUCGCUAUAGCG-3’ (E) 5’-CGCTATAGCGTTT-3’

24. Which of the following peptides has the largest molar extinction coefficient for UV absorption at 280 nm? (A) Tyr-Glu-Gly-Lys (B) Phe-Arg-His-Phe (C) Gln-His-Cys-Ala (D) Val-Asp-Met-Trp (E) Ile-Lys-Asn-Ser

25. What main compound is transported from the cytosol to the mitochondria via malate-aspartate shuttle? (A) NADH (B) NH4 + (C) FADH2 (D) O2 (E) oxaloacetate

26. What enzyme can generate citrulline? (A) NO synthase (B) citrate dehydrogenase (C) citrate oxidase (D) citrulline synthetase (E) citrate peroxidase

27. The Tang Prize in Biopharmaceutical Science was awarded to Dr. Feng Zhang for ________. (A) cancer immunotherapy (B) vesicular transport (C) mitochondrial fusion and fission (D) discovery of nerve growth factor (E) the development of CRISPR/Cas9 as a genome editing platform

28. What amino acid residue is required for the protein region to interact with Src homology 3 (SH3) domain? (A) serine (B) proline (C) lysine (D) arginine (E) leucine

29. Molecular chaperones assist proteins in the formation of ________. (A) aggregates (B) 3° structure (C) amide bonds (D) 1° structure (E) none of the above