4. ______is binding site of RNA polymerase on sequence of DNA. (A) Promoter (B) Operator (C) Binding site (D) Regulator

(5) Which of the followings is most likely to lead to a loss of gene function? (A) A missense mutation in the open reading frame (B) A frameshift mutation in the coding region (C) A change from a T to C in the promoter region (D) A change from a TAA codon to a TAG codon in the coding region (E) A sequence change in the 3' untranslated region