41.56歲女性出現如圖所示病灶,最可能的診斷與最重要的實驗室檢查項目為何?
(A)紅斑性狼瘡(lupus erythematosus);抗核抗體(antinuclear antibodies, ANA)
(B)皮肌炎(dermatomyositis);抗核抗體(antinuclear antibodies, ANA)
(C)紅斑性狼瘡(lupus erythematosus);補體(complement)
(D)皮肌炎(dermatomyositis);肌胺酸激酶(creatine kinase, CK)
答案:登入後查看
統計: A(97), B(92), C(4), D(363), E(0) #3261105
統計: A(97), B(92), C(4), D(363), E(0) #3261105
詳解 (共 5 筆)
#6460044
這題先看選項
基本知識: SLE驗ANA, dermatomyositis驗ck
所以AD二選一,兩個解法:
- 這卷是皮膚科不是風免,而且SLE比較常考discoid rash or butterfly maller rash所以選D
- 不會就去拜拜吧50%正確率
ㅤㅤ
dermatomyositis皮膚表現:
{{c1::heliotroope rash}} (眼皮粉紫色紅斑,伴隨周圍水腫)
{{c1::gottron sign/papule}} (DIP, PIP joint粉色丘疹or 紅斑)
{{c1::heliotroope rash}} (眼皮粉紫色紅斑,伴隨周圍水腫)
{{c1::gottron sign/papule}} (DIP, PIP joint粉色丘疹or 紅斑)
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#6261376
圖為 Gottron sign,在關節 extensor side 有紫紅色斑丘疹(maculopapule);又皮肌炎會侵犯的肌肉,所以病人多可抽血驗到 CK 的上升。
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#6485178
| Feature | Gottron Sign | Inverse Gottron Sign |
|---|---|---|
| Location | Extensor surfaces (e.g., dorsal MCP joints) | Flexor surfaces (e.g., palmar fingers/hands) |
| Appearance | Violaceous or erythematous, scaly lesions | Similar violaceous rash, but on flexor surfaces |
| Associated condition | Dermatomyositis | Dermatomyositis (variant/less common feature) |
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