6.胡先生76歲患有糖尿病、高血壓、慢性腎功能不全及心房顫動於心臟科門診追蹤治療,主訴近兩天頭暈、倦怠及運動後呼吸急促之症狀,在急診測得之心跳呈現不規則每分鐘約為32下,以下何者門診用藥最不可能和其症狀相關?
(A)乙型交感神經阻斷劑(-blocker
(B)毛地黃(digoxin
(C)钙離子通道阻斷劑(calcium chanelblocker
(D)甲型交感神經阻斷劑(a-blocker)
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統計: A(39), B(137), C(37), D(373), E(0) #2741617
統計: A(39), B(137), C(37), D(373), E(0) #2741617
詳解 (共 2 筆)
#6310899
Acute digoxin toxicity
Time course: initial toxic effects of nausea and vomiting occur at 2-4 hours, peak serum levels at 6 hours and life-threatening cardiovascular complications at 8-12h
GI: anorexia, nausea, vomiting, diarrhoea, abdominal pain
METABOLIC: hyperkalaemia (early sign of significant toxicity)
METABOLIC: hyperkalaemia (early sign of significant toxicity)
CVS: enhanced automaticity (atrial tachycardia (e.g. flutter, AF) with AV block, VF, VT, ventricular ectopic beats), bradyarrhythmias (Conduction delays / blocks, slow or regularised AF), hypotension, shock
CNS: lethargy, confusion
Acute toxicity is potentially lethal and digibind is indicated when:
cardiac arrest
life-threatening dysrhythmia
K >5mM
>10mg ingested (adult), >4mg ingested (child)
>15 nM level (>12ng/mL)
cardiac arrest
life-threatening dysrhythmia
K >5mM
>10mg ingested (adult), >4mg ingested (child)
>15 nM level (>12ng/mL)
Nonselective alpha-blockers may cause adverse effects such as hypotension, weakness, tachycardia, and tremulousness.
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