試卷名稱:114年 - 114 學士後醫學系招生考試試題:普通生物及生化概論#126681
年份:114年
科目:學士後西醫-普通生物及生化概論
63. Which of the following statements about thymidylate synthase is correct?
① It catalyzes the conversion of dUMP and N5 ,
-methylene-tetrafolate to dTMP and dihydrofolate.
② It catalyzes the conversion of dUDP and N5 ,
-methylene-tetrafolate to dTDP and dihydrofolate.
③ It catalyzes the conversion of dUMP and N5 ,
-methylene-tetrafolate to dTMP and tetrahydrofolate.
④ 5-Fluorodeoxyuridine monophosphate acts as an irreversible inhibitor of thymidylate synthase.
⑤ 5-Fluorouracil is a reversible inhibitor of thymidylate synthase.
(A) ①④
(B) ①⑤
(C) ②④
(D) ②⑤
(E) ③④