66.下列何者最適合用於預防成人cisplatin引起之腎毒性?
(A)給與2~3 L normal saline
(B)給與aluminum salt
(C)furosemide IV q4h till urine output 100~200 mL/hour
(D)mannitol IV q4h till urine output 100~200 mL/hour
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統計: A(3781), B(74), C(216), D(319), E(0) #1631396
統計: A(3781), B(74), C(216), D(319), E(0) #1631396
詳解 (共 5 筆)
#2898335
5 下列何者為 cisplatin 引起腎毒性之合適預防措施?
(A)給予 2-3 公升之生理食鹽水
(B)給予鋁鹽
(C)每 4 小時給予 furosemide 至尿液達每小時 100-200 mL
(D)每 4 小時給予 mannitol 至尿液達每小時 100-200 mL
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#2927845
特別容易爆腎的病人才需要mannitol
Mannitol is frequently used to induce diuresis, although there is no evidence that this is required. It may be appropriate in select patients, such as those treated with high-dose cisplatin (≥100 mg/m2) and/or those with preexisting hypertension. The addition of furosemide is generally not required, unless there is evidence of fluid overload.
UpToDate Cisplatin nephrotoxicity
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