66.下列對於quinupristin/dalfopristin之敘述,何者錯誤?
(A)Quinupristin為streptogramin type B化合物
(B)Dalfopristin的作用為結合到30S ribosomal subparticle
(C)Quinupristin與dalfopristin一般以30:70 (w/w)比例混合使用
(D)兩種藥物各別使用時具抑菌(bacteriostatic)效果
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統計: A(372), B(2037), C(382), D(680), E(0) #416820
統計: A(372), B(2037), C(382), D(680), E(0) #416820
詳解 (共 10 筆)
#1098978
(B)結合到30S者較少,記:
Tetracyclines
Aminoglycosides
149
2
#980204
Quinupristn
streptogram B
抑菌
Dalforpristin
streptogram A
抑菌
Synercid(R)
quinupristin/dalfopristin=30:70(W/W)
抑制50S 殺菌
61
0
#2284814
Baby很Q,比較年輕,30歲
DAd,比較老,70歲
50
1
#1614697
BBQ ----- streptogram B : Quinupristin
3Q ----- Q:D=3:7
43
0
#2316472
Linezolid是抑制50S上的23S,且抑制70S起始複合物
G(+)為主,用於VER MRSA,但對G(-)無效
抑菌性抗生素,不能用在心內膜炎
避免與高tyramine可能有交互作用
33
0
#835667
quinupristin/dalfopristin 抑制50S ribosomal subunit
16
1
#3078269
Linezolid是一種非選擇的可逆MAOI 所以不能並用Tyramine 否則可能會高血壓危急
15
2
#830872
Quinupristin inhibits the late phase of protein synthesis; dalfopristin inhibits the early phase of protein synthesis.
Treatment of serious or life-threatening infections associated with VREF; treatment of complicated skin and skin structure infections caused by Staphylococcus aureus (methicillin-susceptible) or Streptococcus pyogenes .
Treatment of serious or life-threatening infections associated with VREF; treatment of complicated skin and skin structure infections caused by Staphylococcus aureus (methicillin-susceptible) or Streptococcus pyogenes .
7
1
#4501782
30S ATM(M=3)
Tetracyclines
Aminoglycosides
3
0