85. Researchers used CRISPR-Cas9 to generate a gene knockout clone in mammalian cells. After transfection with Cas9 and sgRNA targeting exon 3 of a gene of interest, they observed frameshift mutations in the target region. Which DNA repair pathway is primarily responsible for generating these frameshift mutations? (A) Base excision repair (B) Nucleotide excision repair (C) Mismatch repair (D) Homology-directed repair (E) Non-homologous end joining

85. Researchers used CRISPR-Cas9 to generate a gene knockout clone in mammalian cells. After transfection with Cas9 and sgRNA targeting exon 3 of a gene of interest, they observed frameshift mutations in the target region. Which DNA repair pathway is primarily responsible for generating these frameshift mutations?
(A) Base excision repair
(B) Nucleotide excision repair
(C) Mismatch repair
(D) Homology-directed repair
(E) Non-homologous end joining

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統計： A(0), B(1), C(0), D(0), E(3) #3853390

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2026/04/01

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核心解析：基因編輯後的「暴力修復」當...

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13. Suppose a person begins breathing very rapidly while resting (hyperventilating), which of the following best describes how homeostasis is restored? (A) Rapid breathing decreases blood CO2 levels, thereby raising blood pH. The frontal cortex detects the change and reduces stimulation of the rib muscles and the diaphragm, thereby decreasing the breathing rate. (B) Rapid breathing increases blood CO2 levels, thereby causing the blood pH to drop. The hypothalamus detects the change and decreases stimulation of the rib muscles and the diaphragm, thereby reducing the breathing rate. (C) Rapid breathing decreases blood CO2 levels, thereby raising blood pH. The hypothalamus detects the change and reduces stimulation of the rib muscles and the diaphragm, thereby decreasing the breathing rate. (D) Rapid breathing increases blood CO2 levels, thereby causing the blood pH to drop. The medulla oblongata detects the change and reduces stimulation of the rib muscles and the diaphragm, thereby decreasing the breathing rate. (E) Rapid breathing decreases blood CO2 levels, thereby raising blood pH. The medulla oblongata detects the change and reduces stimulation of the rib muscles and the diaphragm, thereby decreasing the breathing rate.

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