複選題9. Crystal structures of the transcription elongation complex involving RNA polymerase II reveal a clamp, three loops of the clamp (called the lid, rudder and zipper), and a bridge helix. (A) The function of the lid is to initiate dissociation of the RNA-DNA hybrid. (B) The zipper appears to play a role to maintain the dissociation of the template DNA. (C) The bridge helix appears to play a role to maintain the dissociation of the RNA-DNA hybrid. (D) The rudder is speculated to play a role in translocation during transcription. (E) Alpha-amanitin is bound to a site near the bridge helix appears to enhance translocation during transcription.