4. Which of the following enzymes is the major processive enzyme in leading strand synthesis during eukaryotic DNA replication?
(A) DNA polymerase α (alpha)
(B) DNA polymerase β (beta)
(C) RNA polymerase γ (gamma)
(D) DNA polymerase ε (epsilon)
(E) Telomerase

1. A eukaryotic gene is most likely to be transcribed if it is located where? (A) in the telomeric region of a chromosome (B) in a heterochromatic region of the genome (C) in a euchromatic region of the genome (D) in a region of the genome in which the histones are deacetylated

2. Sister chromatid is: (A) The same thing as homologous chromosomes. (B) A pair of chromosomes of the same kind. (C) Identical copies of the same chromosome attached at the centromere. (D) Always haploid. (E) Always diploid.

3. Which of following RNA participates in ribosome biogenesis? (A) small nucleolar RNA (B) transfer RNA (C) small nuclear RNA (D) microRNA (E) small interfering RNA

5. Which form of DNA damage is least likely to be encountered on a day to day basis? (A) Double strand breaks. (B) Hydroxylation. (C) Deamination. (D) Pyrimidine dimers. (E) Tautomerization.

6. If a replicating cell encounters significant DNA damage during S phase, what is the most likely result? (A) It will arrest in the S phase checkpoint and undergo repair (B) It will immediately trigger apoptosis and die (C) It will utilize telomerase to extend past the damage (D) It will utilize bypass polymerases to complete S phase (E) It will undergo a reductive division

7. Which of the following is not part of a zinc-finger motif? (A) zinc ion (B) proline residue (C) cysteine residue (D) histidine residue

8. Which of the following protein domains would be most likely to recognize and bind to acetylated lysine residues on nucleosomes? (A) homeodomains (B) zinc fingers (C) bromodomains (D) chromodomains

9. Cells, when infected by a DNA virus, can transcribe both stands of the viral DNA and process it into ~21 nt single stranded fragments that can be loaded into protein complexes which target viral protein encoding transcripts for degradation. Which statement below correctly characterizes this process? (A) This siRNA silencing results in a gene knock out. (B) This siRNA silencing results in a gene knock down. (C) This miRNA silencing results in a gene knock out. (D) This miRNA silencing results in a gene knock down. (E) This miRNA silencing results in reversible gene regulation

10. The Central Dogma of molecular biology states that one gene leads to one transcript and results in one protein product. Which of the following processes would refute this dogma? (A) Ordered splicing. (B) RNA editing. (C) Telomerase activity. (D) Translation start site recognition. (E) Polyadenylation of new transcripts.

11. Which of the arrows in the diagram below best represents the position and direction of leading strand DNA synthesis? The vertical bars at the center of the diagram depict the replication origin. (A) A (B) B (C) C (D) D

114年 - [無官方正解]114 國立清華大學_碩士班入學考試試題_生命科學暨醫學院甲組(生物與醫學科學組)：分子生物學#132699

113年 - [無官方正解]113 國立中正大學_碩士班招生考試試題_生物醫學科學系：分子生物學#136961

113年 - 113 國立成功大學_碩士班招生考試_藥理學研究所 :分子生物學#126004

113年 - 112 國立臺灣大學_碩士班招生考試：分子生物學(B)#118906

112年 - 112 國立臺灣大學_碩士班招生考試：分子生物學(C)#120020

112年 - 112 國立臺灣大學_碩士班招生考試：分子生物學(B)#120007

112年 - 112 國立臺灣大學_碩士班招生考試：分子生物學(D)#118608

112年 - 112 國立臺灣大學_碩士班招生考試：分子生物學(A)#118594

112年 - 112 國立清華大學_碩士班考試入學試題_生命科學暨醫學院甲組(生物與醫學科學組):分子生物學#118497

112年 - 112 國立中正大學_碩士班招生考試_生物醫學科學系分子生物:分子生物學#118496