試題詳解

55. The Hsp70 molecular chaperones are a group of proteins that assist nascent protein folding. Which of the following statements about the E. coli Hsp70 is NOT correct?
(A) In Hsp70-assisted folding, the chaperone binds to nascent polypeptide chains while they are still on the ribosomes.
(B) The DnaJ protein binds unfolded proteins during protein synthesis and delivers them to the DnaK: ATP complex.
(C) The Dnak protein recognizes exposed, extended regions of polypeptides that are rich in hydrophilic residues.
(D) Interaction of DnaK with DnaJ triggers the ATPase activity of DnaK. The resulting DnaK: ADP complex forms a stable complex with the unfolded polypeptide.
(E) The reaction cycle requires a nucleotide exchange protein GrpE.