58.能夠反映藥物在體內分佈部位與程度的藥物動力學參數是:
(A)分佈速率常數
(B)半衰期
(C)吸收速率常數
(D)擬似分佈體積
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統計: A(579), B(25), C(116), D(4141), E(0) #537609
統計: A(579), B(25), C(116), D(4141), E(0) #537609
詳解 (共 2 筆)
#4154552
(回樓上) 這是取自於7th課本 CH4
Each indivisual tissue in the body may contain a different concentration of drug due to differences in blood flow and drug affinity for that tissue.
The amount of drug in a given location can be related to its concentration by a proportionality constant that reflects the apparent volume of fluid in which the drug is dissolved.
The volume of distribution represents a volume that must be considered in estimating the amount of drug in the body from the concentration of drug found in the sampling compartment.
也就是說 distribution of apparent volume (Vd)是藥物在體內分布狀況的一個常數,不同部位有不同的藥物濃度,而擬似分布體積就是反應藥物在體內分布濃度 經過估計後得到的量化數據。
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#4154257
求解~~~為何擬似分佈體積 可以反應分布部位?
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