62.評估藥品bioavailability/bioequivalence的方法中,不包括測定下列那個參數?
(A)peak plasma drug concentration
(B)maximum pharmacodynamic effect
(C)renal excretion rate constant
(D)time for maximum urinary excretion
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統計: A(261), B(1341), C(2332), D(1892), E(0) #1631552
統計: A(261), B(1341), C(2332), D(1892), E(0) #1631552
詳解 (共 4 筆)
#2369644
<Applied Biopharmaceutics and Pharmacokinetics> p.476表格
Bioavailability 和 Bioequivalence之數據測量
1. Plasma drug concentration
Tmax : time of peak plasma concentration
Cmax : the peak plasma drug concentration (A)
AUC : the area under the plasma level-time curve
2. Urinary drug excretion data
Du : the cumulative amount of drug excreted in the urine
dDu/dt : the rate of drug excretion
t∞ : time for maximum urinary excretion (D)
3. In vivo pharmacodynamic (PD) comparsion
Emax : maximum PD effect (B)
time for Emax
AUC for PD
onset time for PD
選(C)
340
1
#3442307
不會也可以用推的
(C)renal excretion rate constant (k),應該是用算出來的,無法測得
145
3
#6154261
吸收、分布、排除、腎排除速率常數都沒測
半衰期、清除率、分布體積、最小治療濃度也沒測
0
1