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112年 - 國立臺灣大學_碩士班招生考試_生物化學暨分子生物學研究所:生化學#113391
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題組內容
8. Decide whether the following statements are
True
or
False
, and then explain why. (6%)
5) Loss of the 3' to 5' exonuclease activity of DNA polymerase in E. coli should slow the rate of DNA synthesis but not affect its fidelity.
相關申論題
6) Pyrimidine dimmers are usually formed between two thymines in different strands.
#484618
9. Abnormalities in the catalytic activities of key enzymes are commonly linked to diseases. Please describe (at least) three possible causes that may lead to abnormal enzyme activities (6%).
#484619
1) serine protease (2%)
#484620
2) allosteric regulation (3%)
#484621
3) prosthetic group (2%)
#484622
4) competitive inhibitor (3%)
#484623
11. How do you experimentally determine the Vmax (maximum velocity) and KM (Michaelis constant) of an enzyme? (4%)
#484624
12. Write all you know about a membrane bilayer. What is it for? What is it made of? What are its chemical constituents? What properties does it have? What are the methods to study its properties? What are its functions? How do its constituents work for its functions? (8%)
#484625
13. Describe the figure below. Note: it starts from amino acids. What are the diseases associated with it? How does one deal with the diseases? Can the urea cycle work alone? What are the roles of oxaloacetate? What does the cell do when oxaloacetate is used up by the urea cycle? (8%)
#484626
1) 5' modification.
#484627
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